KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX38
All Species:
12.12
Human Site:
T250
Identified Species:
20.51
UniProt:
Q92620
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92620
NP_054722.2
1227
140503
T250
E
R
S
H
R
L
S
T
R
D
R
D
R
S
V
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
R172
D
E
W
E
R
T
E
R
E
R
L
Q
D
L
E
Rhesus Macaque
Macaca mulatta
XP_001097681
1323
150587
T346
E
R
S
H
R
L
S
T
R
D
R
D
R
S
V
Dog
Lupus familis
XP_536800
1226
140550
S249
D
R
S
H
R
Q
S
S
R
D
R
D
R
S
V
Cat
Felis silvestris
Mouse
Mus musculus
A2A4P0
1244
142553
G294
A
I
G
D
I
Y
N
G
K
V
T
S
I
M
Q
Rat
Rattus norvegicus
Q5XI69
779
88496
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025753
1230
141019
R249
E
R
S
H
R
A
S
R
D
I
D
R
R
D
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_957170
1258
143711
R273
D
R
S
E
R
S
Q
R
S
V
R
D
S
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572947
1222
139562
T252
K
S
D
W
D
M
P
T
P
R
R
H
G
N
K
Honey Bee
Apis mellifera
XP_001122500
1093
125136
T221
E
R
K
A
S
G
A
T
P
S
I
E
G
E
E
Nematode Worm
Caenorhab. elegans
P34498
1131
129405
E237
D
R
E
W
Y
D
N
E
G
A
F
D
D
E
Y
Sea Urchin
Strong. purpuratus
XP_786478
1200
137247
N247
P
N
T
L
R
R
Q
N
D
F
S
E
R
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
Y267
V
K
R
D
M
E
V
Y
V
K
V
I
S
I
S
Baker's Yeast
Sacchar. cerevisiae
P15938
1071
121634
L199
L
P
E
E
A
K
L
L
P
V
I
R
N
I
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37
92.2
97.7
N.A.
37.7
22.6
N.A.
N.A.
89.8
N.A.
81.3
N.A.
62.3
58.1
55.5
68.4
Protein Similarity:
100
53.7
92.6
99.1
N.A.
55.7
37.3
N.A.
N.A.
95.1
N.A.
89.9
N.A.
77.3
72.1
71.3
81
P-Site Identity:
100
6.6
100
80
N.A.
0
0
N.A.
N.A.
46.6
N.A.
33.3
N.A.
13.3
20
13.3
20
P-Site Similarity:
100
13.3
100
93.3
N.A.
13.3
0
N.A.
N.A.
46.6
N.A.
40
N.A.
33.3
33.3
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.1
36.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.3
55
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
8
8
8
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
29
0
8
15
8
8
0
0
15
22
8
36
15
8
15
% D
% Glu:
29
8
15
22
0
8
8
8
8
0
0
15
0
22
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% F
% Gly:
0
0
8
0
0
8
0
8
8
0
0
0
15
0
0
% G
% His:
0
0
0
29
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
8
0
0
8
0
0
0
0
8
15
8
8
15
0
% I
% Lys:
8
8
8
0
0
8
0
0
8
8
0
0
0
0
8
% K
% Leu:
8
0
0
8
0
15
8
8
0
0
8
0
0
8
0
% L
% Met:
0
0
0
0
8
8
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
8
0
0
0
0
15
8
0
0
0
0
8
8
0
% N
% Pro:
8
8
0
0
0
0
8
0
22
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
15
0
0
0
0
8
0
0
8
% Q
% Arg:
0
50
8
0
50
8
0
22
22
15
36
15
36
0
15
% R
% Ser:
0
8
36
0
8
8
29
8
8
8
8
8
15
29
8
% S
% Thr:
0
0
8
0
0
8
0
29
0
0
8
0
0
0
0
% T
% Val:
8
0
0
0
0
0
8
0
8
22
8
0
0
0
22
% V
% Trp:
0
0
8
15
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
8
0
8
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _